Web.Config - Cannot read configuration file due to insufficient permissions

[Adr2ien]

I am getting the error:\[code\]Module IIS Web CoreNotification UnknownHandler Not yet determinedError Code 0x80070005Config Error Cannot read configuration file due to insufficient permissionsConfig File \\?\C:\inetpub\wwwroot\web.config\[/code\]The file itself has full permissions for IUSR. IIS is running its app pool under ApplicationPoolIdentity. I did a file monitor on the file, and I see this:\[code\]9:04:43.8035456 AM w3wp.exe 8104 CreateFile C:\inetpub\wwwroot\Web.config ACCESS DENIED Desired Access: Generic Read, Disposition: Open, Options: Synchronous IO Non-Alert, Non-Directory File, Attributes: N, ShareMode: Read, AllocationSize: n/a\[/code\]No idea why I am getting this error... Any ideas?