i use ASP.Net 4, this code for open local file (this site is iis local and 25.docx file in local)address file:\[code\]\\shear_file\Site\Files\25.docx\[/code\]link:\[code\] <a href="file://///shear_file/Site/Files/25.docx" >25</a>\[/code\]if run site with iis and click on link. its not open! but save this page and open page Stored and click on link. its open open file!!and use this code:\[code\]Response.Redirect(@"file://///shear_file/Site/Files/25.docx");\[/code\]not open file!