If an item in the dropdown list is selected

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How do I write an if statement that states:
IF an item in my dropdown list is selected THEN....

I've got this:
If questionddl.SelectedValue = True Then

But it's not working...

Thanks loads Or better still how would I say:

IF an item in my dropdown list is selected (excluding the first item [which is the title]) THEN....you can try
If questionddl.SelectedValue <> the Default option(the title in our case) THEN
...
..
EndifExcellent thanks!